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WHY VALA
SCREENING SERVICES
PRODUCTS
- KIC®
  
  Kinetic Image Cytometer®
- CyteSeer®
  
  Automated Video Analysis Software
- ValaDATE™ AI
  
  Deep Analytics for Toxicity & Efficacy
- SIM®
  
  Structured Illumination Microscopy
- Cells & Reagents
  
  Fully validated antibodies, reagents, screening kits and hiPSC-derived cells.
PUBLICATIONS

Application NotesRick Gregory2023-04-26T21:46:07+00:00

Application Notes

CARDIOMYOCYTES

Single-cell interleaved voltage-calcium imaging to quantify drug effects on hiPSC-cardiomyocyte electrophysiology

Direct quantification of pharmaceutical effects on cardiac action potentials in human stem cell-derived cardiomyocytes

Simultaneous detection of action potentials and contractility in human stem cell-derived cardiomyocytes

See related video below.

View Video of cardiomyocyte voltage and contractility traces

Measuring contractility, calcium transients, and sarcomere shortening in adult canine cardiomyocytes treated with omecamtiv mecarbil

See related videos below.

View Video of intersarcomeric distance measurements

View Video of cardiomyocyte contractility and calcium transient measurements

NEUROSCIENCE

Measuring voltage activity in hiPSC-dopaminergic neurons using Kinetic Image Cytometry®

See related videos below.

View voltage transients recorded with Vala’s IC200-KIC® (Figure 2)

View synchronous voltage transients recorded with Vala's IC200-KIC® (Figure 5)

Measuring calcium transients in hiPSC-glutamatergic neurons using Kinetic Image Cytometry®

See related video below.

View video of calcium transients recorded with Vala's IC200-KIC® (Figure 4)

View 5-hour time-lapse video of Vala's hiPSC-microglia engulfing zymosan beads.

View 24-hour time-lapse video of Vala's hiPSC-microglia engulfing amyloid beta oligomers

CANCER

Measuring E-cadherin localization in HT-29 human colon cancer cells