KIC is a leap forward in cellular imaging, combining ultra-fast videography with high-throughput analytics that see and measure the effects of a dosed therapeutic candidate in real time on each of thousands of living cells simultaneously, to discern curative or detrimental effects with the highest sensitivity.
Video cytometry also incorporates the concept of “slow motion”, wherein recordings of events such as millisecond action potentials are played back more slowly to enable visualization.
Vala’s IC200-KIC utilizes sCMOS cameras to acquire high-speed videos (at a maximum of 1500 frames per second) of fluorescent indicators, which are then processed by the CyteSeer ® Analysis Software Platform to extract about 30 measurements of the morphologies of each transient of each cell. KIC is fully compatible with high throughput (HT) robotics and can be integrated into an existing HT workstation.
With automation, KIC can screen up to 7000 wells per day (in 96 or 384 well plates).