Dr. Augustin oversees Vala’s instrument manufacturing, quality control, and hardware and technical support, bridging the gap between biologists and engineers involved in basic science, drug discovery, and screening. He is an expert in image processing, particularly automated image analysis for high-throughput microscopy and high-content screening. He has practical experience with a variety of imaging techniques such as confocal laser-scanning microscopy, deconvolution microscopy, as well as with flow cytometry. Dr. Agustin also has extensive experience doing tissue culture for mammalian cell lines and optimizing immunofluorescence. He has implemented QC workflows for evaluating autofocus performance and image quality for automated microscopes, especially Z-factor and SSMD for high-content screening. Dr. Agustin has implemented algorithms to correct for illumination distortion and chromatic aberration and have developed methods to do image registration among multiple cameras that corrects for translation, rotation, and magnification differences.
Dr. Augustin holds a B.S from University of California, Davis in Mechanical Engineering, and M.S. in Mechanical Engineering from MIT, and an M.S. and Ph.D. in Bioengineering from University of California, San Diego